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Diet plus insulin compared to diet alone in the treatment of gestational diabetes mellitus: a systematic review BJMBR
Giuffrida,F.M.A.; Castro,A.A.; Atallah,A.N.; Dib,S.A..
Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be expected from insulin therapy in preventing fetal complications in these patients. In a systematic review of the literature assessing the efficacy of insulin in preventing macrosomia in fetuses of mothers with gestational diabetes, we found six randomized controlled trials comparing diet alone to diet plus insulin. The studies included a total of 1281 patients (644...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Diabetes; Gestational; Diet therapy; Fetal macrosomia; Insulin; Meta-analysis.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000004
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Quality of life and adherence to treatment in early-treated Brazilian phenylketonuria pediatric patients BJMBR
Vieira Neto,E.; Maia Filho,H.S.; Monteiro,C.B.; Carvalho,L.M.; Tonon,T.; Vanz,A.P.; Schwartz,I.V.D.; Ribeiro,M.G..
Early dietary treatment of phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, results in normal cognitive development. Although health-related quality of life (HRQoL) of PKU patients has been reported as unaffected in high-income countries, there are scarce data concerning HRQoL and adherence to treatment of PKU children and adolescents from Brazil. The present study compared HRQoL scores in core dimensions of Brazilian early-treated PKU pediatric patients with those of a reference population, and explored possible relationships between adherence to treatment and HRQoL. Early-treated PKU pediatric patient HRQoL was evaluated by self- and parent-proxy reports of the Pediatric Quality of Life Inventory (PedsQL) core scales. Adherence...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phenylketonuria; Quality of life; Questionnaires; Patient compliance; Diet therapy.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000200613
Registros recuperados: 2
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